# Buffalo Bills Play Thursday Night vs Division Rival: What to Know About NFL Week 2 Game ## Bills' First Home Game of 2022 Season, Divisional Clash The Buffalo Bills are set to host their first home game of the 2022 season on Thursday Night Football against their AFC East rivals, the Tennessee Titans. The game is scheduled to begin at 8:15 p.m. ET on NFL Network. The Bills are coming off a 31-10 victory over the Los Angeles Rams in Week 1, while the Titans lost 21-20 to the New York Giants. ## Key Storylines to Watch ### Bills Look to Continue Offensive Success The Bills' offense looked impressive in their season-opening win over the Rams. Quarterback Josh Allen threw for 297 yards and three touchdowns, while running back James Cook rushed for 117 yards and a touchdown. The Titans' defense will be a tough test for the Bills' offense. Tennessee allowed just 21 points to the Giants in Week 1, and they have a strong pass rush led by Harold Landry and Jeffery Simmons. ### Titans Need to Improve Offensive Line Play The Titans' offensive line struggled in their Week 1 loss to the Giants. Quarterback Ryan Tannehill was sacked six times, and the running game was held to just 77 yards. The Bills' defense is one of the best in the NFL, led by All-Pro cornerback Tre'Davious White and linebacker Matt Milano. The Titans will need to improve their offensive line play if they want to have any chance of winning this game. ### Divisional Rivalry Adds Extra Intensity The Bills and Titans are division rivals, and there is always extra intensity when these two teams meet. The Bills have won the last two meetings between the teams, including a 34-7 victory in Nashville last season. The Titans will be looking to avenge those losses and get their season back on track. The Bills will be looking to continue their strong start to the season and take an early lead in the AFC East. ## Prediction The Bills are a 6.5-point favorite in this game, and they should be considered the favorite to win. They have a more talented roster, and they are playing at home. However, the Titans are a tough team, and they will be looking to make a statement in their first road game of the season. This game could be close, but the Bills should be able to pull out a victory.
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